Identification of a B cell activation specific enzyme
نویسندگان
چکیده
منابع مشابه
HIV-1-specific B cell activation. A major constituent of spontaneous B cell activation during HIV-1 infection.
B cell activation is a well known consequence of HIV-1 infection, and seropositive subjects show high numbers of spontaneously activated Ig-secreting cells in circulation. To better define the importance of the HIV-1-specific response in this phenomenon, we first studied whether in vitro spontaneous anti-HIV-1 antibody production was accompanied by reactivation of memory B lymphocytes. Unstimul...
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Low-level expression of multiple lineage-specific genes is a hallmark of hematopoietic stem cells (HSCs). HSCs predominantly express genes specific for the myeloid or megakaryocytic-erythroid lineages, whereas the transcription of lymphoid specific genes appears to begin after lymphoid specification. It has been demonstrated for a number of genes that epigenetic priming occurs before gene expre...
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ژورنال
عنوان ژورنال: Arthritis Research & Therapy
سال: 2000
ISSN: 1478-6362
DOI: 10.1186/ar-2000-66856